Under the guidance of the principle of “national organization，alliance procurement，platform operation”，the joint quantity procurement of “4+7” pilot cities has in fact evolved into national drug quantity procurement. This is the first time in the history of centralized drug procurement in China to organize，mobilize and implement quantity procurement at the national level. It has a profound impact on pharmaceutical manufacturers，and because of its associated butterfly effect，it will deeply influence the operating modes of the entire chain，all links and full life circle of China’s pharmaceuticals industry. The pharmaceutical distribution industry，which is an important link to the health industry value chain and the medicine supply chain，is no exception. The pharmaceutical distribution industry is facing the most profound and complex policy environment in history，and is likely to be at the time node of transformation and even historical changes.