This report first analyzed the logic of virtual-high drug prices and supporting medicine with drug，and it was the monopoly of public medical institutions and the regulation on medical services and pharmaceutical price，nevertheless the root was that the public health care system and the market economy were incompatible. Then the important policies introduced in 2016 were reviewed，and it found that promoting the industry merger and acquisition，improving the industry concentration have become the main trend of the pharmaceutical industry and the pharmaceutical distribution industry；moreover，centralized drug procurement and “Two-Invoice System” were boosting the separation of pharmacy from medicine. The situation of the slower growth of government receipts and the tight of the medical insurance fund has become a reform window，what is more，the business model innovation led by the new technology has become the booster for pharmaceutical separation. Under these multiple factors，the separation of pharmacy from medicine may become the lever to leverage the reform，and bring significant opportunities to medical industry，pharmaceutical industry，as well as pharmaceutical distribution industry.