The Yellow River Basin plays a very important role in China’s economic and social development and ecological security. It gathers the cultural characteristics and cultural resources of provinces and cities along the Yellow River Basin，and also has common culture and regional characteristics. The development of cultural industries in the Yellow River Basin is one of the main ways to inherit and carry forward the Yellow River culture and revitalize the economy of provinces and cities along the Yellow River Basin. There are some problems in the development of cultural industries in the Yellow River Basin，such as the lag of top-level design，the imperfection of policy system，the low degree of integration of regional resources and the low degree of brand identification of cultural enterprises. In order to better promote the development of cultural industries in the Yellow River Basin，we should build a regional structure of “one belt，three centers，three regions，and multi nodes”，and improve the multi-dimensional policy system，to realize the integration of “Yellow River ecological industrial belt +” cross-border strategic purpose，we should cultivate multi-level talents in cultural industries，and focus on the development mode of “Yellow River ecological industrial belt + creative cultural products”.