As an important engine of China’s economic and social development，the cultural industries in the Yangtze River Delta region has maintained steady development trend and market vitality. The added value of cultural industries has increased year by year. The pillar industry has played a significant driving effect and has become the first section in the development of China’s cultural industries. Artificial intelligence，night tour economy，cultural and tourism integration，digital content and integrated development have become the “Keywords” of the Yangtze River Delta culture. The Yangtze River Delta region has grasped the opportunity and trend of economic development at present. With its unique regional geographical environment，economic environment，cultural environment，policy environment and its own development strength，the Yangtze River Delta region has successfully established itself in the six world-class urban agglomerations and kept pace with the times. In December 2019，the Outline Development Plan for Regional Integration of the Yangtze River Delta was issued，which proposed that the Yangtze River Delta region should be built into the most influential and dynamic growth pole，and become an important institutional guarantee for the high-quality development of cultural industries integration in the Yangtze River Delta. Under the national strategies，the great development of the cultural industries in the Yangtze River Delta not only ushers in new opportunities，but also faces new challenges. On the whole，it advances towards the direction of high-quality integration led by structural optimization and innovation.