Under the development background of increasingly scarce land resources，shifting to stock development land through urban regeneration is an important way for the future development of our cities. Guangzhou has also issued relevant policies and regulations in recent years to promote urban regeneration. This article starts from the interpretation of the connotation of urban regeneration，taking the policy characteristics and existing problems in different periods in the evolution of Guangzhou’s urban regeneration policy as the starting point，analyzes the new problems reflected in the implementation of the project after the introduction of the regeneration policy in recent years（2019-2020），interprets Regeneration policies for 9 cities in the Guangdong-Hong Kong-Macao Greater Bay Area，analyzes the impact of the construction of the Guangdong-Hong Kong-Macao Greater Bay Area on Guangzhou’s urban regeneration，and combines domestic and foreign urban regeneration policy formulation and implementation experience to propose the optimization ideas of Guangzhou’s urban regeneration policies in the context of the Guangdong-Hong Kong-Macao Greater Bay Area，in order to provide reference for future Guangzhou urban regeneration policy formulation work.