Improving the modernization level of the industrial chain is a major strategic plan made by the Central Committee of the Communist Party of China （CCCPC） with Comrade Xi Jinping at the core in the face of changes for development at home and abroad. It is of great significance for promoting the optimization and upgrading of the economic system，enhancing the control and safety of the industrial chain，and improving economic quality and performance and core competitiveness. By studying the implication and requirements of the industrial chain modernization，this paper analyses the basic conditions，opportunities and challenges for Zhongshan City to improve the modernization level of the industrial chain in the context of the great pattern of the Guangdong-Hong Kong-Macao Greater Bay Area. Learning from the experience of other domestic cities in improving the modernization level of the industrial chain，the overall guideline，several relationships that need to be managed，strategies and suggestions of improving the modernization level of the industrial chain of Zhongshan City are proposed.