The rapid development of social economy puts forward new requirements for high-level talents in the future，and colleges and universities are faced with the opportunities and challenges of talent training. Nanyang Institute of Technology adheres to the concept of “innovation leads entrepreneurship，entrepreneurship creates more jobs” and forms a unique “1 plus 3 plus X” entrepreneurship education model. The practice of Nanyang Institute of Technology shows that colleges and universities should focus on the integration of production and education，the mutual assistance of schools and enterprises to educate people，actively carry out innovative and entrepreneurial education reform，so as to improve the success rate of students’ entrepreneurship，create more jobs and promote the development of local economy.