The biomedical industry has high growth，strong correlation and strong driving force，which can promote the agglomeration of related industries and effectively drive the innovation and development of related industries with the help of the technology-intensive characteristics. By constructing coupling degree and coupling coordination degree models，this report measures the integration degree of biomedical industry chain and innovation chain in Beijing-Tianjin-Hebei region from the dimensions of changes in the scale of manufacturing and innovation，changes in development vitality，changes in innovation driving force，and changes in the coupling coordination degree of the two systems. Study found that Beijing-Tianjin-Hebei biomedical industry innovation link of manufacturing support role in the development of the whole is gradually enhanced，manufacturing and innovation link fusion results overall rising steadily，but there is a large gap in the industrial development of various regions，and the innovation resources present an obvious “dual core” distribution pattern. Most cities do not have in the foundation for the development of the local better realize the double chain integration，it is necessary to promote the coupling development of local industrial chain and innovation chain with the help of the radiation power of innovation in Beijing and Shijiahzuang. Based on this，this report puts forward the following countermeasures and suggestions：build a multi-agent information integration exchange platform for the Beijing-Tianjin-Hebei biomedical industry，pay close attention to the construction of a number of public facilities for research and development，build a “pyramid” innovation chain development pattern，and improve the efficiency of transformation of scientific and technological achievements in multiple dimensions，etc.