This study analyze the current situation of the integration of the industrial chain and the innovation chain in Beijing，Tianjin and Hebei. Combined with the formation and evolution law of the industrial chain，industrial chain from the urban agglomeration in the key nodes of space layout of the situation，sources of comparative advantage in key industries，evolution characteristics of industrial chain in urban agglomeration，the study found that In the Beijing-Tianjin-Hebei urban agglomeration，Cangzhou，Baoding and Xingtai have more core nodes in the manufacturing industry chain；the formation of comparative advantage industries in Tianjin，Tangshan，Zhangjiakou and Chengde is closely related to their location conditions；Cangzhou’s industrial policy plays an obvious role in promoting the development of the key nodes in its industrial chain. At the same time，the integration of the Beijing-Tianjin-Hebei industrial chain and the innovation chain also faces some problems：In the industrial chain of Beijing-Tianjin-Hebei，the proportion of “strong point” sectors that gain comparative advantage through technological innovation is low；the integrity of the industrial chain in a small number of cities shows a downward trend，which leads to the extension of the distance between industries within the original industrial chain；the lack of key hub nodes in the Beijing-Tianjin-Hebei industry chain is not conducive to the development of downstream industries；the development of node cities in urban agglomeration is insufficient；In the process of the integration of high-tech manufacturing and producer services，there exists a high degree of separation between the two sectors. There is a significant gap between the diffusion environment of innovation source and innovation destination，which restricts the improvement of the output efficiency of technological achievements. Based on this，put forward countermeasures and suggestions：explore and implement the “chain length” system for the industry chain around the ten most advanced，sophisticated and sophisticated industries；promote the diffusion of Beijing’s technological achievements in related fields to the industries with comparative advantages in surrounding areas；further improve the environment for the diffusion of innovation achievements in innovation destinations within urban agglomerations；complementing the pivot industries extending from the “backbone chain” to the “branch chain” of the industrial chain，consolidating the evolution foundation of the industrial chain；within the Beijing-Tianjin-Hebei urban agglomeration，cultivate and build three to five key node cities integrating industrial chains and innovation chains.