Hilton is the top brand in the global hotel industry. Hilton Guangzhou Science City is located in the central area of the Science City，Guangzhou，the capital of Guangdong Province. This paper first introduces the basic information of the hotel，the products and services it provides. And then explores the successful operation of the hotel from four aspects：customer service strategy，human resource management strategy，digital strategy and corporate image strategy. Finally，the hotel’s future promotion plan is analyzed.