The construction of an innovative metropolitan area is an important measure in the new historical stage to enhance regional competitiveness，optimize the allocation of regional innovation factor resources，and accelerate the transformation and upgrading of regional industries. The construction of the Zhengzhou metropolitan area into an innovative metropolitan area has a good practical foundation，but there are also constraints such as uneven distribution of innovation resources，poor internal connections of innovation elements，low innovation efficiency，and insufficient institutional mechanisms. In the future，to build an innovative Zhengzhou metropolitan area，efforts should be made to strengthen the construction of a collaborative innovation industry system，continue to attract and gather high-end scientific and educational resources，accelerate the improvement of innovative and entrepreneurial platform carriers，build an efficient and interconnected transportation network，and improve the governance system of the metropolitan area.