As a means of strategic containment unilaterally provoked by the US against China’s rapid rise，the Sino-US trade friction not only affects bilateral trade，but also has a heavy impact on Chinese enterprises’ overseas investment. Based on this，this section firstly analyzes the influence mechanism of the trade friction on the overseas investment of Chinese enterprises on the basis of sorting out the event context of Sino-Us trade friction，and evaluates the specific influence of the trade friction on the overseas investment of Chinese enterprises. To go further，this section also summarizes the status quo of overseas investment of Chinese enterprises. Finally，the section puts forward the overall plan and key layout of Chinese enterprises’ overseas investment under the context of Sino-US trade friction. The study is of certain reference significance for Chinese enterprises to continue to execute the “Go Global” strategy，to respond to the “The Belt and Road” initiative，to actively participate in the global value chain competition，and to seek new breakthroughs in overseas markets across trade barriers under the new situation of Sino-US trade friction.