Theindustrial foundation and Opening-up advantages of Guangdong-Hong Kong-Macao Greater Bay Area is obvious. Against the context that China’s economy has shifted from being pulled from trade dividend to domestic demand，the key to the coordinated development of the Greater Bay Area is Hong Kong and Macao’s integrating into the overall development of the country，so as to give full play to bilateral comparative advantages and to release the dividends of market integration further. To achieve collaborative development，we need to synchronize the “hard docking” and the “soft docking”，promote the “four collaborative paths” with the “four systems construction” as the core，and break the bottlenecks restricting the collaborative development of the Greater Bay Area.