This chapter will study the changes of the five major international innovation and entrepreneurship indexes in recent years，and provide a broader international perspective on the current situation and challenges of China’s innovation and entrepreneurship. This chapter explores the structure and connotation of the Global Innovation Index，Innovation Cities Index，Global Entrepreneurship Monitor，Global Startup Ecosystem Report，and Global Entrepreneurship Index. It is found that in recent years，China’s investment in innovation and entrepreneurial resources has gradually increased. The environment for both innovation and entrepreneurship has been continuously optimized，and the output of knowledge creation and innovation has increased year by year. China has maintained a good upward trend in innovation and entrepreneurship.