Cancer is a serious disease that seriously threatens the health of Chinese residents. With the change of population aging，the incidence of cancer increases year by year，and the prevention and control of cancer has become an important part of the healthy construction of China. In order to achieve the goal of preventing and controlling cancer，we should adhere to the principle of prevention，strengthen comprehensive prevention and control，and promote the transformation of disease treatment to health management. The healthy city is an effective platform for the comprehensive management of social health in our country. It is a feasible plan to combine cancer prevention and cure with healthy city organically and realize the combination of prevention and control，prevention and control，and special group. Research shows that healthy city cancer prevention and control action should push forward the following aspects：promote the combination of groups and pieces，form an effective organization management system；adhere to the combination of specific groups，actively control cancer risk factors；strengthen the combination of prevention and control，strengthen early screening and early diagnosis and treatment；standardize the diagnosis and treatment of cancer，continuously enhance the ability of medical services；integrate traditional Chinese medicine and western medicine，give full play to the advantages of traditional Chinese medicine；lead by information technology to enhance the overall cancer management ability and level；promote deep fusion of production and research and research. The implementation path is to establish organizational leadership and working mechanism，formulate work plan and special technical guide，advance pilot step by step，carry out effect evaluation and progress assessment.