The healthy and safe operation of the city is an important premise and guarantee for Shanghai to become an outstanding global city and a socialist modern international metropolis with world influence. Through the construction of systematic urban safety risk monitoring and early warning system，scientific and strict urban safety management prevention and control network，efficient urban safety emergency response system，comprehensive and effective urban safety multiple governance system and safety supervision and defense line in relevant key areas，Shanghai has continuously strengthened urban safety and governance innovation，effectively improved the urban safety management system and the modernization level of governance capacity，which provides valuable experience for the safety governance of super large cities.