From the perspective of the global competition pattern of e-commerce channels，listed companies such as Amazon and eBay occupy the mainstream competitive position in European and American markets，while listed companies such as Alibaba occupy the mainstream competitive position in China and Southeast Asian countries. This report selects 12 typical cross-border e-commerce listed companies around the world. Through the comparative analysis of the core financial data，financial indicators，operation status，development strategy and corporate social responsibility of these listed companies. This paper comprehensively presents the operation and development level of listed enterprises. And then it puts forward the distribution and development trend of cross-border e-commerce industry. Finally，the report puts forward the layout and development trend of cross-border e-commerce industry. It is concluded that cross-border e-commerce will help upgrade the industrial chain，promote the two-way investment of Chinese and foreign capital，and will play a positive role in the domestic and international dual cycle.