2019 is known as the first year of e-commerce live broadcasting. E-commerce live broadcast is a new business model that redefines and effectively links people，markets and goods. It can effectively compress the intermediate links，reshape the transaction mode，and improve the profits of enterprises. It can play an important role in helping the transformation process of Guangzhou professional wholesale market. This paper makes a comprehensive and in-depth analysis of the current situation and existing problems of the transformation and upgrading of Guangzhou e-commerce live broadcasting enabling professional wholesale market，and puts forward the future development ideas，that is，promote industrial docking and promote the deep integration of e-commerce live broadcast and professional wholesale market；Deeply cultivate the supply chain and promote the upgrading of the industrial base and the modernization of the industrial chain in the professional wholesale market；Strengthen government services and vigorously create a business environment suitable for the development of e-commerce live broadcast，etc.