Based on the analysis of the development foundation，the problems and facing the situation in the twelfth five-year plan，the paper proposes general ideas of the development of Guangzhou in the period of the twelfth five-year plan. Guangzhou shall insist on six strategic directions on paying more attention to the transformation of the mode of economic development，combining explanding domestic demand with stabilizing foreign demand，the green development，the development of urban and rural regional integration，improving the people’s livelihood and first test.it urges economy and soliety of Guangzhou to deuelop in the round.