Skilled talents are the core and most basic labor element connecting technological innovation and production practice. At present，under the background of a new round of technological revolution，China’s economy has entered a new era of high-quality development stage. Manufacturing industry is in transition. The supporting effect of skilled talents on economic industry is more prominent，and We must build a team of skilled talents with sufficient quantity，excellent quality and reasonable structure as soon as possible. From the perspective of new technology revolution and supply side structural reform，this paper analyzes the new requirements of high-quality development for skilled personnel in the new era and the problems faced by the development of skilled talents in terms of quantity，quality，structure，configuration，institutional mechanisms，etc. In view of the construction of skilled personnel team to adapt to high-quality development，policy suggestions and measures are put forward from the legal construction of vocational skills development，monitoring，planning，evaluation，use，education and training，incentive guarantee and other key links.