From the outside，the strong guidance and support of national and local laws and policy systems，the urgent need for economic and social development and scientific and technological progress，the severe pressure of employment and competition for students，and the strong stimulus of public opinion prejudice and identity discrimination are all influencing and stimulating the endogenous driving force for the reform and development of private colleges and universities. From internal view，understanding and mastering the private colleges reform deep endogenous power should focus on seven aspects：Beginner’s mind and mission of the founder，system mechanism and flexible advantage，market oriented educational concept，the keen awareness of seizing development opportunities，the natural genes of innovation and entrepreneurship，the unique campus culture and spiritual tradition，and the urgent need for teachers and staff to pursue fair and high-quality development and so on. In 2019，private colleges and universities in Henan Province have made remarkable achievements in vigorously promoting the high-quality development of party construction and ideological and political work，coordinating and promoting the construction of technology-based universities，and continuously improving their social service capabilities. But there are also some problems，such as relatively backward construction of first-class undergraduate major，outstanding short board of high-level talents，weak ability of discipline competition between teachers and students，incomplete participatory governance system and unreasonable assessment and incentive system. In this regard，private colleges and universities in Henan Province should continue to improve the modern university system，constantly innovate the school system and mechanism，gradually build a pattern of multiple participation，thoroughly implement the concept of innovative development，vigorously improve the assessment and incentive methods，actively cultivate the characteristic university culture，release the endogenous driving force of reform furtherly，and achieve high-quality development.