Air quality is of vital importance to the survival and health of residents，and air pollution has posed a serious threat to the healthy living of urban residents. It is of great significance to establish an evaluation system of urban healthy living based on air quality to improve urban air quality and residents healthy living. This report describes the air quality the important influence to the residents health living，focus on the national 113 key environmental protection cities as the research object，especially in environmental health indicators include PM2.5 annual average concentration，PM10 annual average concentration，air quality to reach and is better than two days three reaction of air quality indicator，constructed based on air quality evaluation index system of urban health living，to has carried on the comprehensive evaluation of 113 key environmental protection cities，and the evaluation results are analyzed in depth.