Antibiotics are a typical contaminant of drugs and pharmaceutical and personal care products（PPCPs）. Trace antibiotics can not only have a direct ecotoxicological effect on organisms，but also induce microorganisms to produce drug resistance genes，causing the spread of resistance genes in the environment，which has a serious impact on the environment and human health. Our country is one of the major antibiotic producing countries，and the discharge of pharmaceutical wastewater below standards is one of the main sources of antibiotics in the environment. This report systematically summarized the current status of trace antibiotics in the environment in China，discussed the application of membrane separation technology in antibiotic wastewater，and predicted the application of new composite membranes in antibiotic wastewater treatment.