In 2019，the industrial output value of Shenzhen exceeded that of Shanghai for the first time，standing the highest among other large and medium-sized cities in China. The industrial investment maintained at rapid growth. High-end manufacturing continued to develop in a fast track. Enterprise competitiveness continuesd to improve with the continuously well-performing benefits. In 2020，the industrial economy of Shenzhen will face more severe and complicated challenges. Therefore，Shenzhen should seize the major opportunities brought about by GBA （Guangdong-Hongkong-Macao Greater Bay Area） and the Shenzhen Demonstration Pilot Zone for socialism with Chinese characteristics. At the same times，a new round of science technological revolution and industrial revolution has brought about the Window Opportunity. Shenzhen should continue to enhance the quality of industry and enterprise development. Efforts should be spared to push forward the quality revolution，efficiency revolution and dynamic revolution in the manufacturing industry.