The report made an introduction about the price performance such as CPI and PPI in Shenzhen 2019. Comparative studies were conducted herein on the prices among Shenzhen and other first-tier cities in Guangdong province and others in China. The underlying reasons for the price fluctuation was therefore analyzed. Under the influence of the COVID-19 and the monetary policies，proposals were made to create a profound monetary and financial circumstances at macro level for the high-quality economic development. In terms of the policies at meso level，the “combined” efforts shall be made among different governmental departments. The pressures on the disadvantaged group exerted by the rising price shall be alleviated in micromanagement to ensure the social security. According to the report，Shenzhen should intensify the monitoring on the price pressure at grass-root level. The stablized price should be listed into an requirement in the high-quality development.