As the most important innovation resource，talent resources play a key role in the construction of an innovative city in Xiongan New Area. By retrieving and analyzing the WeChat public account big data of talents in Xiongan New Area，and using the method of content analysis to explore the multi-subjects and their relationship structure in the process of talent resource reconstruction in Xiongan New Area，and divide them into core-level subjects，auxiliary layer subjects and edge layer subjects，and compared and analyzed. The study found that with the development of the Xiongan New Area，the government’s administrative intervention has declined，but the change has not changed too much，and the market has not yet played a major role. Among the auxiliary stratum，financial institutions are active entities，but their performance is not outstanding. The weight coefficient of edge layer subjects is the smallest，which reflects that the construction of public service system and living security is insufficient. Furthermore，from the perspective of optimizing the multi-subjects and their relationships in the reconstruction of talent resources in Xiongan New Area，this paper puts forward specific suggestions in order to promote the construction of an innovative city in Xiongan New Area.