The Guangdong-Hong Kong-Macao Greater Bay Area was first written in the “Government Work Report” in 2017 and has now become a key area for China’s development and construction in the new era. Although the Guangdong-Hong Kong-Macao Greater Bay Area construction plan has only been started for a short time，it has achieved remarkable results in promoting regional economic and social development. However，in comparison with the three traditional bay areas in the world，there is still a gap between the current status of Guangdong-Hong Kong-Macao Greater Bay Area and the long-term construction goals of the “Global Fourth-largest Bay Area” and “Global High-Tech Innovation Heights”. The ability to attract all kinds of outstanding talents and optimize regional innovation resources has a huge strategic significance for the long-term development of the Guangdong-Hong Kong-Macao Greater Bay Area. This article proposes that although the current situation of the Guangdong-Hong Kong-Macao Greater Bay Area is generally progressive and the attractiveness to talents is growing，there are still four major problems：internal differentiation of talent attractiveness，imbalance of talent structure，lack of entrepreneurial talents，and shortage of international high-end talents. These problems objectively restrict the long-term development of the Bay Area. In order to better solve the above problems，this article puts forward a series of policy recommendations aimed at accelerating the introduction of high-level talents in the Guangdong-Hong Kong-Macao Greater Bay Area and optimizing the environment for innovation and entrepreneurship.