Digital economy represents a new trend in global economic innovative development，it has become a new engine for the economic development in Guangdong-Hong Kong-Macao Greater bay area. The Greater bay area，mainly led by Guangzhou-Shenzhen-Hong Kong，is increasingly capable of scientific and technological innovation since digital talents in the bay area largely support economic vitality. However，“data barriers” and insufficient digital education resources are still the shortcomings of the digital economy in the Greater bay area. Digital economy is of great practical significance to the innovative development of the Greater bay area，bringing new opportunities to its innovative development，providing strong strategic support to its innovative development，and promoting the optimization and upgrading of its industrial structure. Digital technology has become an important driving force for industrial innovation and upgrading in the Greater bay area. Digital technology drives industrial innovation and upgrading in multiple-level，multi-dimensional and multi-type ways，and it is the standard configuration for the industrial innovation and upgrading of the Greater Bay Area. Driven by market demand，digital technology promotes the deep integration of digital technology and industries in the greater bay area，which creates an ecosystem to co-share big data. Led by digital technology，digital trade become an important part of the digital economy of the greater bay area and strengthens its international market position，digital trade will give greater vitality to the innovative development in the greater bay area.