The world-class urban agglomerations in the Guangdong-Hong Kong-Macao Greater Bay Area are built under effect of core city poles. Among the four core engines of the Greater Bay Area，Guangzhou is a national central city and a comprehensive gateway city. With its gateway function，comprehensive transportation hub，rich industrial categories，advantages of international business centers，talent training and supply levels，and cultural tolerance，Guangzhou has created a good condition for gathering international resources and realizing regional and international radiative influence in the Greater Bay Area. From a forward-looking perspective，Guangzhou will continue to strengthen its external communication capabilities，corporate innovation capabilities，and attractive features to further enhance the quality and level of its pole-driven functions. At the same time，from the research of the four major factors of economy，technology，education and environment，it can be expected that Guangzhou will continue to play a vital role in leading development in the Guangdong-Hong Kong-Macao Greater Bay Area.