Medical device complaint management is an important part of the quality management system of distributing companies. The establishment of a sound complaint management system is not only the requirement of regulations but also to monitor the safety and effectiveness of products and help manufacturers to continuously improve the quality of products so as to continuously improve customer satisfaction. As a multinational enterprise operating in China as well as an agent of MAH in China，it is very important to timely and accurately collect and transmit complaint information to foreign manufacturing companies. The purpose of this article is to share some experiences of multinational companies in complaint management，including：complaint collection，reporting，adverse event judgment，complaint investigation，customer communication and other aspects，so as to throw out a brick to attract a jade.