Objective：the purpose of this paper is to provide relevant reference materials for industry research through the analysis of the performance of domestic A-share medical device listed companies in different fields. Methods：through the statistics of the annual report data disclosed by listed companies，the core financial indicators of these companies were analyzed. Results：due to the differences in the main business，products，technical advantages and industry barriers of listed medical device companies，there are differences in financial indicators such as gross profit margin and return on net assets. Through the analysis of the financial indicators of listed companies，we can also evaluate the operating performance of the above-mentioned companies. Conclusion：high gross profit rate products are mainly used in the fields of high value orthopedic consumables and IVD. These products have core patents and industry barriers，thus creating extremely high net profit margins.