During the 40 years of Reform and Opening，China’s medical device industry has made great progress and development，establishing the industrial clusters of the Pearl River Delta，the Yangtze River Delta and the Bohai Bay. The construction of the industrial chain of medical device is basically complete and the supply chain tends to be structurally balanced，moreover the value chain is during the period which is from the mid-low end to the mid-high end. Due to the endogenous demand of enterprises has a new understanding and attention to the “going out” and participation in the “Belt and Road” initiative，it is inevitable that enterprises will strengthen the introducing of new technology products during internationalization of domestic market and develop strategies of expanding market share in terms of product accessibility and marketization during domestication of international market. Therefore it has led to the requirement to complement market experience and deal with risks in international cooperation.