In defining the weight determination，the present author of this report adopts an entropy evaluation method to measure the integrative development of thirteen urban areas in each of which a CBD is located. The conclusion indicates that from 2013 to 2017，the development of CBD in cities of China is steady，but the development is unbalanced between the first-tier cities and the new first-tier cities. The overall score of the first-tier cities is higher than that of the new first-tier cities. By analyzing the sub-indexes of economic growth，economic driving，technological innovation，social development and regional radiation，we can find obvious differences exist between the CBDs of the first-tier cities and those of the new first-tier cities. Generally speaking，CBD development of the first-tier cities is better than that of the new first-tier cities，showing different development trends in the two types of cities. On the basis of measurement result，the author combines the development stages，the characteristics of China’s CBD and the background of its further opening. She believes that CBD should become an engine of the high-level opening of China’s economy and take the responsibility to push the regional economy cross the pass. CBD development will give a development profit to surrounding areas and help to promote the infra-structure construction and build broad channels for opening trade business to the outside world. Meanwhile，the development will improve the opening capability of related cities by offering high-level internationalized talents.