This report analyzes the first-mover advantages and development obstacles of rural revitalization in the Yangtze River Delta region. In order to give full play to the dual overlapping effect of the national rural revitalization strategy and the Yangtze River Delta regional integration strategy，the Yangtze River Delta region should have a higher position. This report puts forward some suggestions，including continuously enhancing the industrial competitiveness，accelerating the pace of enriching people’s income，establishing a new trend of ecological civilization，enhancing the level of rural governance，and increasing policy support. Let the Yangtze River Delta region explore the way for the national high-quality rural integration and revitalization.