The system of evaluating index of economic growth quality is constructed on the base of analysis of the quality of economic growth connotation in the Yangtze River Delta region （YRD） by the quality of inputs dimension，the efficiency of allocation dimension，and technological progress dimension. The YRD is focused as research object in this paper. The quality of economic growth connotation in the YRD from 1991 to 2016 is measured and analyzed by principal component analysis. The results show that the economic growth of YRD would continue to decline，it is still in the factor-driven and capital-driven stage，its innovation driven potential is huge. It is put forward to promote the quality of economic growth of YRD，by optimizing the factor quality improvement system，guiding the high-level factor concentration，and creating the benefit oriented soft environment advantage.