Developing green manufacturing and adjusting the traditional industrial structure will not only alleviate overcapacity，stimulate the energy efficiency of the Yangtze River Economic Belt manufacturing industry，but also deepen the international influence of the Yangtze River Economic Belt manufacturing industry. This report quantitatively examines the overall characteristics of energy consumption in the Yangtze River Economic Belt manufacturing industry. It is found that the main energy consumption of the Yangtze River Economic Belt is generally on the rise. The industrial energy consumption is dominated by coal and oil，and natural gas consumption has shown rapid growth in recent years. The regional energy consumption structure of the Yangtze River Economic Belt has a large regional difference，and the energy intensity is also declining. This report uses Kaya’s identity to measure CO₂ emissions，and decomposes CO₂ emission factors by LMDI addition decomposition method. The measurement results show that the carbon emissions of energy consumption in the Yangtze River Economic Belt are generally rising，and the scale of the industry and population are expanding. The rapid economic growth and continuous adjustment of the energy structure and the year-on-year reduction in energy efficiency are the main reasons for the rapid growth of carbon emissions in the Yangtze River Economic Belt. After 2013，the industrial structure upgrading of the Yangtze River Economic Belt and the advancement of energy-saving technologies have promoted the adjustment of industrial energy consumption structure and energy efficiency，which has led to an increase in the economic development level of the Yangtze River Economic Belt. However，this strong decoupling state is not stable.