The opening of the Hong Kong-Zhuhai-Macao Bridge and the development strategy of the Guangdong-Hong Kong-Macao Great Bay Area have brought about opportunities to upgrade transportation channels，cooperation mechanism，and industrial system in the cities of Zhuhai，Hong Kong，and Macao，which opened a new model for collaboration in the Great Bay Area. Therefore，the cooperation path between Zhuhai，Hong Kong，and Macao will be built around the construction of the Hong Kong-Zhuhai-Macao Bridge，the development of the Guangzhou-Shenzhen-Hong Kong-Macao Science and Technology Innovation Corridor and the cooperation of Hengqin Island. A closer exchange and cooperation platform based on improving the cooperation mechanism between Zhuhai and Macao is particularly needed. Based on the innovative cooperation model of Zhuhai，Hong Kong，and Macao，we will vigorously cultivate new cooperation carriers. With the strengthened of the interconnection of transportation infrastructure，elements flow among the three cities will be more convenient and efficient. With the deepened cooperation in the fields of social welfare and people’s livelihood，we will jointly build the Great Bay Area as a model for a livable，suitable，and visitor-friendly Bay Area.