Culture and tourism are the important content and carrier of the construction of Guangdong-Hong Kong-Macao Great Bay Area. The Development Plan for Guangdong-Hong Kong-Macao Great Bay Area sets precise requirements for the coordinated development of Guangdong，Hong Kong，and Macao，which requires to deepen the integration of cultural tourism in the Great Bay Area. Achieving high-quality development offers great space and opportunities. Since 2018，the Great Bay Area has developed rapidly in fields like research travel，construction of cultural innovative park，night travel economy，film and television music，and common culture market，presenting a large number of new forms of cultural travel，finance，and technology. Guangdong，Hong Kong，and Macao have joined hands to expand opening-up. The prospects for cooperation in the construction of the “Belt and Road，” participation in international exchanges and collaboration，and opening up the global market，therefore，have become extremely broad. Undoubtedly，the successful construction of the Humanistic Bay Area will become a beautiful window for China to present its cultural confidence to the world.