With a comprehensive industrial systems，obvious cluster advantages，and a high degree market openness and internationalization，Guangdong，Hong Kong，and Macao all enjoy the basic conditions and advantages of collaboratively building a modern industrial system. However，due to various factors，the Great Bay Area faces many challenges in advancing its international competitiveness. In the future，Guangdong-Hong Kong-Macao Great Bay Area should give full play to their respective industry comparative advantages，promote the free flow of resources and complement mutual strengths，promote industrial integration and development，jointly create world-class industrial clusters，and together build a modern industrial system with international competitiveness，and finally become a model for High-Quality Development.