After entering the New Era，the development of Guangdong Province demands more intelligence support from the university think tanks. However，the reform of university think tanks in Guangdong still faces numerous difficulties. Our research confirms that university think tanks in Guangdong have contributed to industrial upgrade，building open economy，construction of the Greater Bay Area，and the stability of social security network. However，we also find that the quantity of high-standard university think tanks is limited，the quality of their research is compromised，the existence of institutional obstacles is prevalent，and the channels of exerting social influence are unsatisfying. Therefore we propose some policy recommendations. First，we should promote institutional reform，including reforms of reviewing，employing and financing mechanism. Second，we should optimize research products，including strengthening cooperation with other think tanks，insisting on data-driven analysis，and joining market competition. Third，we should upgrade the channel of social communications，including promoting marketing activities，sharing the research result with the society in innovative ways，and maintaining proper right of speech in international research.