Drug usage in Europe now encompasses a much wider range of substances than in the past. Among drug users，mixed drug consumption is common and individual patterns of usage range from experimental to habitual to hard-core addiction. The prevalence of cannabis use is about five times that of other substances. While the use of heroin and other opioids remains relatively rare，they continue to be the drugs most commonly associated with the more harmful methods such as injection. Overall use of drugs is generally higher among males，and this difference is in addition accentuated by patterns of more intensive and regular use.