Integrated circuits for space flight systems should not only deal with extremely harsh temperature，vibration and other environments，but also deal with ubiquitous cosmic radiation，which requires high anti-radiation performance of integrated circuits. Radiation-resistant integrated circuits are the key core electronic components of space flight systems. They are regarded as important strategic resources by foreign countries，and export control is strictly controlled. At present，the level of anti-radiation integrated circuits in our country lags far behind that in the United States，Europe and other countries and regions，and we need to make greater efforts to break through this bottleneck.