Japan first established a national policy to promote the use of generic drugs in 2002. The research and development capabilities，manufacturing capabilities，and process technologies of various generic drug manufacturers in Japan were different. It was important to ensure low prices and high quality through collaboration，and continue to produce high value-added products by reducing the burden of taking medicines through introducing new dosage forms and simplifying. Generic manufacturers must ensure a stable and continuous supply of medicines. Generic drugs were required to be consistent with brand-name drugs on quality，and to achieve the stable supply of high-quality generic drugs at low prices，which was not only the mission of the generic drug companies but also a social responsibility. It was of great significance to infiltrate such cognition and spirit into the corporate culture of generic drug manufacturers.