The promotion of coordinated regional development is a new demand for China to implement major strategies that cater to changes in both domestic and international environment，and a natural choice to advance the transformation and upgrading of regional economic and social development. The report analyzes the historical process of Anhui’s involvement in the integration of Yangtze River Delta，summarizes its major practices and restrictions，and proposes policy recommendations for Anhui to further involve in higher quality integration of Yangtze River Delta in the new era.