Under the background of significant lack of land resources and unsustainable ecological environment，optimizing the land stock and changing the development mode have become one of the main impetuses to promote industrial transformation and upgrading. Firstly，this paper reviews the process of land redevelopment in 26 cities of urban agglomeration in Yangtze River Delta，and divides it into three stages：the initial stage（1997-2006），the exploratory stage（2007-2012）and the upgrading stage（2013-present）. Then the land use intensity of urban agglomeration in Yangtze River Delta is evaluated by using the entropy model and efficacy function. It is divided into three types：high-intensive-land-use city，intensive-land-use city and low-intensive-land-use city. It is found that the land use of urban agglomeration in Yangtze River Delta has a large spatial difference，showing a “center-periphery” structure，and the land use structure of each city is not completely reasonable. Finally，on the basis of learning from and comparing the experience of land redevelopment in Shenzhen and Nanhai，the paper puts forward the path and strategy of industrial transformation and upgrading for the cities with different land use intensity：promoting the integrated development of urban agglomeration planning in the Yangtze River Delta，constructing the mutual promotion mechanism of land stock optimization and industrial transformation and upgrading；high-intensive-land-use cities paying attention to the construction of land ecological environment and cultivation and development of strategic emerging industries；intensive-land-use cities optimizing land supply and actively introducing high value-added industries；low-intensive-land-use cities implementing differentiated land use policies to accelerate the transformation of economic momentum.