At present，the world economy and trade is in an important period of transformation and reconstruction，regional trade system arrangement has become an inevitable trend of world economic development. The state council has approved the establishment of 12 pilot free trade zones in the east coast and inland areas，giving priority to a series of pilot free trade zones in investment，trade，finance and other fields. The “One Belt And One Road” initiative brings new opportunities for the development and opening up of China’s border areas. Border area is the zone with rich underground resources，surface and space resources. Given full play to the special advantage of border area，to establish a free trade zone，will make the “peripheral” areas into “vanguard” of the reform and opening up，and change the overall situation of reform and national development.