Regional science popularization cooperation is an important channel for promoting the level of regional science popularization effectively，improving the science popularization quality of regional citizens，exploring regional economic new-growth points，fostering regional independent innovation in science and technology，and also realizing the comprehensive development of regional science popularization. As a Role with strongest power in Beijing-Tianjin-Hebei region，Beijing should play a leader in the regional science popularization cooperation of Beijing-Tianjin-Hebei. This report discusses the classic cases，which demonstrate regional science popularization cooperation of Beijing，Tianjin and Hebei in recent years，through annual science popularization data under different indicators in these three regions，from the perspective of development，science popularization in Beijing，its leading，driving and serving of coordinated Development for Beijing-Tianjin-Hebei Region has been analyzed seriously，and also putting forward the countermeasures and suggestions.