This report describes and analyzes the operating status of Zhongguancun NEEQ enterprise from the perspective of operating revenue，gross profit，net profit and period expense. At the same time，in order to exclude the impact of new listed companies on the number of indicators，this report further studied the operating conditions of the continuous listed enterprises in 2016-2017.According to the report conclusion，in 2017，under the overall depressed situation of the NEEQ market in China，the operating income，gross profit，net profit and other indicators of the NEEQ enterprises in Zhongguancun continued to rise，and the innovative-level enterprises were more prominent，highlighting the growth of their operating performance. At the same time，the overall trend of various period expense ratio showed a slow decline，indicating that the management and sales costs of the NEEQ enterprises in Zhongguancun were gradually effectively controlled，the overall quality of the business income of the enterprises was improved，and their profitability was enhanced. The analysis of continuous listed enterprises in 2016-2017 shows similar characteristics to the whole.