Through questionnaire，in-depth interview and field research，this paper discusses health information seeking behavior and its determinants of Africans in Guangzhou，and tries to offer certain advices on health promotion strategies.The survey results find that female Africans and those with higher educational background，stronger influences by health information and higher self efficacy tend to seek health information more actively.While certain demographic features such as age and living time in Guangzhou have no significant influences in health information seeking behavior.The survey also finds that the initiative of health information seeking has positive correlation with health promotion effect.Through the qualitative field research，the study analyses the organizations and their works of health promotion，and also how Africans get access to and participate health promotion campaigns.The research，based on the findings，proposes strategic advices on health promotion campaigns of Africans in Guangzhou，which include：health promotion planning should match the Africans' group features，consider their health information seeking behavior and relied more on public medical institutions to play more important role.