Due to its inefficiency and trust problems，the existing supply chain needs to introduce new technology to solve its inherent contradictions.The boom of virtual currency in recent years has triggered the exploration of the application of blockchain，and the fusion effect of blockchain and supply chain is urgently needed for further research.After analyzing the development of the supply chain，this report analyzes the defects and deficiencies of the current supply chain.Then，this report studies the relevant characteristics of blockchain，summarizes the unique advantages of blockchain application supply chain on this basis，and provides examples of logistics and multi-agent transaction application.Finally，the shortcomings of efficiency privacy and other aspects of the application supply chain of blockchain are discussed，and the relevant solutions are prospected.